New blog post on ComputeCancer blog!
I’ve just added a new post on my ComputeCancer blog. This time I wrote about estimating minimal time on PD-1/PD-L1 inhibitors for successful tumor regression.
And here is a brief intro:
“In todays post, I will adopt a mathematical model that was introduced by Kuznetsov and colleagues back in 1994 (Kuznetsov et al., Bull Math Biol, 1994) to investigate the effects of anti-PD-1/PD-L1 therapy depending on the pretreatment tumor characteristics. The way in which the model was formulated more than two decades ago allows for elegant and straightforward incorporation of such a treatment. I will show how the variability in the observed response dynamics is explained by the model and how can we estimate the minimal time on PD-1/PD-L1 treatment required for a therapeutical success.”